Gene description for Sumo2
Gene name SMT3 suppressor of mif two 3 homolog 2 (yeast)
Gene symbol Sumo2
Other names/aliases SUMO-2
Smt3A
Smt3b
Smt3h2
Species Mus musculus
 Database cross references - Sumo2
ExoCarta ExoCarta_170930
Entrez Gene 170930
UniProt P61957  
 Sumo2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Sumo2
Molecular Function
    SUMO transferase activity GO:0019789 IDA
    poly(A) RNA binding GO:0044822 ISO
    ubiquitin protein ligase binding GO:0031625 ISO
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IGI
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 ISO
    negative regulation of transcription, DNA-templated GO:0045892 ISO
    cellular protein localization GO:0034613 ISO
    protein sumoylation GO:0016925 ISO
Subcellular Localization
    PML body GO:0016605 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Sumo2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Sumo2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sumo2 is involved
No pathways found





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