Gene description for Erdr1
Gene name erythroid differentiation regulator 1
Gene symbol Erdr1
Other names/aliases edr
Species Mus musculus
 Database cross references - Erdr1
ExoCarta ExoCarta_170942
Entrez Gene 170942
 Erdr1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Erdr1
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    somatic stem cell maintenance GO:0035019 IDA
    negative regulation of cell proliferation GO:0008285 IDA
    negative regulation of cell migration GO:0030336 IDA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Erdr1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Erdr1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Erdr1 is involved
No pathways found





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