Gene description for Usp15
Gene name	ubiquitin specific peptidase 15
Gene symbol	Usp15
Other names/aliases	Ubp109
Species	Rattus norvegicus
Database cross references - Usp15
ExoCarta	ExoCarta_171329
Vesiclepedia	VP_171329
Entrez Gene	171329
UniProt	Q9R085
Usp15 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Usp15

Molecular Function     cysteine-type endopeptidase activity GO:0004197 IEA     cysteine-type endopeptidase activity GO:0004197 ISO     cysteine-type endopeptidase activity GO:0004197 ISS     cysteine-type deubiquitinase activity GO:0004843 IDA     cysteine-type deubiquitinase activity GO:0004843 IEA     cysteine-type deubiquitinase activity GO:0004843 ISO     transforming growth factor beta receptor binding GO:0005160 IEA     transforming growth factor beta receptor binding GO:0005160 ISO     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     SMAD binding GO:0046332 IEA     SMAD binding GO:0046332 ISO     ubiquitin-modified histone reader activity GO:0061649 IEA     ubiquitin-modified histone reader activity GO:0061649 ISO     deubiquitinase activity GO:0101005 ISO     K48-linked deubiquitinase activity GO:1990380 IEA     K48-linked deubiquitinase activity GO:1990380 ISO Biological Process     proteolysis GO:0006508 IEA     transforming growth factor beta receptor signaling pathway GO:0007179 IEA     transforming growth factor beta receptor signaling pathway GO:0007179 ISO     protein deubiquitination GO:0016579 IDA     protein deubiquitination GO:0016579 IEA     protein deubiquitination GO:0016579 ISO     BMP signaling pathway GO:0030509 IEA     BMP signaling pathway GO:0030509 ISO     BMP signaling pathway GO:0030509 ISS     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IEA     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISS     monoubiquitinated protein deubiquitination GO:0035520 IEA     monoubiquitinated protein deubiquitination GO:0035520 ISO     monoubiquitinated protein deubiquitination GO:0035520 ISS     transcription elongation-coupled chromatin remodeling GO:0140673 IBA     transcription elongation-coupled chromatin remodeling GO:0140673 IEA     transcription elongation-coupled chromatin remodeling GO:0140673 ISO     transcription elongation-coupled chromatin remodeling GO:0140673 ISS     positive regulation of RIG-I signaling pathway GO:1900246 IEA     positive regulation of RIG-I signaling pathway GO:1900246 ISO     regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 IEA     regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 ISO     negative regulation of antifungal innate immune response GO:1905035 IEA     negative regulation of antifungal innate immune response GO:1905035 ISO     negative regulation of antifungal innate immune response GO:1905035 ISS     protein K27-linked deubiquitination GO:1990167 IEA     protein K27-linked deubiquitination GO:1990167 ISO     protein K27-linked deubiquitination GO:1990167 ISS Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 IEA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     nuclear body GO:0016604 IEA     nuclear body GO:0016604 ISO