Gene description for Mgst1
Gene name microsomal glutathione S-transferase 1
Gene symbol Mgst1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Mgst1
ExoCarta ExoCarta_171341
Vesiclepedia VP_171341
Entrez Gene 171341
UniProt P08011  
 Mgst1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Mgst1
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    glutathione transferase activity GO:0004364 IDA
    glutathione transferase activity GO:0004364 IEA
    glutathione transferase activity GO:0004364 ISO
    glutathione transferase activity GO:0004364 TAS
    glutathione peroxidase activity GO:0004602 IEA
    glutathione peroxidase activity GO:0004602 ISO
    identical protein binding GO:0042802 IDA
    identical protein binding GO:0042802 IPI
    glutathione binding GO:0043295 IDA
Biological Process
    glutathione metabolic process GO:0006749 ISO
    response to xenobiotic stimulus GO:0009410 IDA
    response to lipopolysaccharide GO:0032496 IDA
    Leydig cell differentiation GO:0033327 IEP
    glutathione transport GO:0034635 IEA
    glutathione transport GO:0034635 ISO
    cellular response to lipid hydroperoxide GO:0071449 IEA
    cellular response to lipid hydroperoxide GO:0071449 ISO
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 ISO
    mitochondrial outer membrane GO:0005741 IDA
    mitochondrial outer membrane GO:0005741 IEA
    peroxisomal membrane GO:0005778 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    membrane GO:0016020 IDA
    apical part of cell GO:0045177 IDA
 Experiment description of studies that identified Mgst1 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Mgst1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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