Gene description for Dcxr
Gene name dicarbonyl L-xylulose reductase
Gene symbol Dcxr
Other names/aliases glb
Species Rattus norvegicus
 Database cross references - Dcxr
ExoCarta ExoCarta_171408
Entrez Gene 171408
UniProt Q920P0  
 Dcxr identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Dcxr
Molecular Function
    L-xylulose reductase (NADP+) activity GO:0050038 ISO
    oxidoreductase activity, acting on CH-OH group of donors GO:0016614 ISO
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655 ISO
Biological Process
    glucose metabolic process GO:0006006 ISO
    protein homotetramerization GO:0051289 ISO
    D-xylose metabolic process GO:0042732 IEA
    NADP metabolic process GO:0006739 ISO
    xylulose metabolic process GO:0005997 ISO
    oxidation-reduction process GO:0055114 ISO
Subcellular Localization
    brush border GO:0005903 ISO
    membrane GO:0016020 IEA
    microvillus GO:0005902 ISO
    extracellular exosome GO:0070062 ISO
    cytoplasmic microtubule GO:0005881 ISS
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Dcxr in exosomes
1
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Dcxr
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dcxr is involved
No pathways found





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