Gene description for Masp1
Gene name mannan-binding lectin serine peptidase 1
Gene symbol Masp1
Other names/aliases AW048060
Species Mus musculus
 Database cross references - Masp1
ExoCarta ExoCarta_17174
Entrez Gene 17174
UniProt P98064  
 Masp1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Masp1
Molecular Function
    protein homodimerization activity GO:0042803 ISO
    hydrolase activity GO:0016787 IEA
    peptidase activity GO:0008233 IEA
    calcium ion binding GO:0005509 ISO
    serine-type peptidase activity GO:0008236 IEA
    serine-type endopeptidase activity GO:0004252 ISO
    metal ion binding GO:0046872 IEA
    calcium-dependent protein binding GO:0048306 ISO
Biological Process
    complement activation GO:0006956 IEA
    innate immune response GO:0045087 IEA
    complement activation, lectin pathway GO:0001867 IMP
    immune system process GO:0002376 IEA
    proteolysis GO:0006508 IDA
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Masp1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Masp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Masp1 is involved
No pathways found

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