Gene description for Mug1
Gene name murinoglobulin 1
Gene symbol Mug1
Other names/aliases -
Species Mus musculus
 Database cross references - Mug1
ExoCarta ExoCarta_17836
Entrez Gene 17836
UniProt P28665  
 Mug1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Mug1
Molecular Function
    peptidase inhibitor activity GO:0030414 IEA
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
    endopeptidase inhibitor activity GO:0004866 IEA
Biological Process
    negative regulation of peptidase activity GO:0010466 IEA
    embryo implantation GO:0007566 IGI
Subcellular Localization
    extracellular space GO:0005615 IEA
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified Mug1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Mug1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mug1 is involved
No pathways found





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