Gene description for Mup1
Gene name major urinary protein 1
Gene symbol Mup1
Other names/aliases Ltn-1
Lvtn-1
Mup-1
Mup-a
Mup10
Mup7
Up-1
Species Mus musculus
 Database cross references - Mup1
ExoCarta ExoCarta_17840
Vesiclepedia VP_17840
Entrez Gene 17840
 Mup1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Mup1
Molecular Function
    insulin receptor activity GO:0005009 IDA
    pheromone activity GO:0005186 IDA
    odorant binding GO:0005549 IBA
    pheromone binding GO:0005550 IDA
    small molecule binding GO:0036094 IEA
Biological Process
    energy reserve metabolic process GO:0006112 IDA
    mitochondrion organization GO:0007005 IDA
    insulin receptor signaling pathway GO:0008286 IEA
    aerobic respiration GO:0009060 IDA
    cellular response to starvation GO:0009267 IEP
    positive regulation of gene expression GO:0010628 IDA
    negative regulation of lipid storage GO:0010888 IDA
    positive regulation of glucose metabolic process GO:0010907 IDA
    heat generation GO:0031649 IDA
    response to stilbenoid GO:0035634 IEP
    glucose homeostasis GO:0042593 IMP
    locomotor rhythm GO:0045475 IDA
    negative regulation of gluconeogenesis GO:0045721 IDA
    positive regulation of lipid metabolic process GO:0045834 IDA
    negative regulation of DNA-templated transcription GO:0045892 IDA
    negative regulation of lipid biosynthetic process GO:0051055 IDA
    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IDA
    negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 IDA
    cellular response to food GO:0071240 IEP
    cellular response to testosterone stimulus GO:0071394 IEP
    cellular response to lipid GO:0071396 IDA
Subcellular Localization
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IDA
    extracellular space GO:0005615 ISO
    nucleus GO:0005634 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Mup1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Mup1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mup1 is involved
No pathways found





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