Gene description for Neo1
Gene name neogenin
Gene symbol Neo1
Other names/aliases 2610028H22Rik
AI327052
D930014N22Rik
Igdcc2
Species Mus musculus
 Database cross references - Neo1
ExoCarta ExoCarta_18007
Entrez Gene 18007
 Neo1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Neo1
Molecular Function
    receptor activity GO:0004872 IPI
    protein binding GO:0005515 IPI
    cadherin binding GO:0045296 IDA
Biological Process
    cell adhesion GO:0007155 IEA
    negative regulation of neuron death GO:1901215 ISO
    negative regulation of protein secretion GO:0050709 IDA
    regulation of transcription, DNA-templated GO:0006355 IDA
    iron ion homeostasis GO:0055072 ISO
    myoblast fusion GO:0007520 IMP
    positive regulation of BMP signaling pathway GO:0030513 IGI
Subcellular Localization
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    neuronal cell body GO:0043025 ISO
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Neo1 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Neo1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Neo1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here