Gene description for Nrxn2
Gene name neurexin II
Gene symbol Nrxn2
Other names/aliases 6430591O13Rik
mKIAA0921
Species Mus musculus
 Database cross references - Nrxn2
ExoCarta ExoCarta_18190
Entrez Gene 18190
 Nrxn2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nrxn2
Molecular Function
    calcium channel regulator activity GO:0005246 IGI
    protein binding GO:0005515 IPI
Biological Process
    synapse assembly GO:0007416 IGI
    neurotransmitter secretion GO:0007269 IGI
    vocalization behavior GO:0071625 ISO
    adult behavior GO:0030534 ISO
    synaptic transmission GO:0007268 IGI
    vocal learning GO:0042297 ISO
    social behavior GO:0035176 ISO
Subcellular Localization
    presynaptic membrane GO:0042734 ISA
    protein complex GO:0043234 IPI
    cell GO:0005623 IGI
 Experiment description of studies that identified Nrxn2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nrxn2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nrxn2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here