Gene description for Ddr2
Gene name	discoidin domain receptor family, member 2
Gene symbol	Ddr2
Other names/aliases	AW495251 Ntrkr3 tyro10
Species	Mus musculus
Database cross references - Ddr2
ExoCarta	ExoCarta_18214
Entrez Gene	18214
UniProt	Q62371
Ddr2 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Ddr2

Molecular Function     collagen binding GO:0005518 ISO     transferase activity GO:0016740 IEA     protein tyrosine kinase collagen receptor activity GO:0038062 ISO     transferase activity, transferring phosphorus-containing groups GO:0016772 IEA     nucleotide binding GO:0000166 IEA     protein kinase activity GO:0004672 IEA     protein tyrosine kinase activity GO:0004713 IEA     transmembrane receptor protein tyrosine kinase activity GO:0004714 ISO     ATP binding GO:0005524 IEA     kinase activity GO:0016301 IEA Biological Process     transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 IDA     protein phosphorylation GO:0006468 IEA     regulation of bone mineralization GO:0030500 ISO     protein autophosphorylation GO:0046777 ISO     positive regulation of fibroblast migration GO:0010763 IMP     phosphorylation GO:0016310 IEA     chondrocyte proliferation GO:0035988 IMP     ossification GO:0001503 IEA     biomineral tissue development GO:0031214 IMP     positive regulation of fibroblast proliferation GO:0048146 IMP     positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 ISO     positive regulation of cell proliferation GO:0008284 IMP     collagen fibril organization GO:0030199 IMP     peptidyl-tyrosine phosphorylation GO:0018108 ISO     collagen-activated tyrosine kinase receptor signaling pathway GO:0038063 ISO     endochondral bone growth GO:0003416 IMP     positive regulation of extracellular matrix disassembly GO:0090091 IMP     positive regulation of osteoblast differentiation GO:0045669 ISO     positive regulation of protein kinase activity GO:0045860 ISO Subcellular Localization     membrane GO:0016020 IEA     integral component of plasma membrane GO:0005887 IEA     focal adhesion GO:0005925 ISO     plasma membrane GO:0005886 IEA     apical plasma membrane GO:0016324 ISO     extracellular exosome GO:0070062 ISO     integral component of membrane GO:0016021 IEA