Gene description for Per3
Gene name period circadian clock 3
Gene symbol Per3
Other names/aliases 2810049O06Rik
mPer3
Species Mus musculus
 Database cross references - Per3
ExoCarta ExoCarta_18628
Entrez Gene 18628
UniProt O70361  
 Per3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Per3
Molecular Function
    protein binding GO:0005515 IPI
    kinase binding GO:0019900 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
    signal transducer activity GO:0004871 IEA
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    circadian rhythm GO:0007623 IDA
    rhythmic process GO:0048511 IEA
    circadian regulation of gene expression GO:0032922 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA
    regulation of circadian sleep/wake cycle, sleep GO:0045187 ISO
    transcription, DNA-templated GO:0006351 IEA
    signal transduction GO:0007165 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Per3 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Per3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Cry1  
Affinity Capture-Western Mus musculus
2 Arntl  
Affinity Capture-Western Mus musculus
3 Per1  
Affinity Capture-Western Mus musculus
4 Cry2  
Affinity Capture-Western Mus musculus
5 Csnk1e  
Affinity Capture-Western Rattus norvegicus
6 Clock  
Affinity Capture-Western Mus musculus
7 Per2  
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Per3 is involved
No pathways found





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