Gene description for ECHS1
Gene name enoyl CoA hydratase, short chain, 1, mitochondrial
Gene symbol ECHS1
Other names/aliases ECHS1D
SCEH
Species Homo sapiens
 Database cross references - ECHS1
ExoCarta ExoCarta_1892
Entrez Gene 1892
HGNC 3151
MIM 602292
UniProt P30084  
 ECHS1 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for ECHS1
Molecular Function
    enoyl-CoA hydratase activity GO:0004300 TAS
    protein binding GO:0005515 IPI
Biological Process
    cellular lipid metabolic process GO:0044255 TAS
    fatty acid beta-oxidation GO:0006635 TAS
    small molecule metabolic process GO:0044281 TAS
Subcellular Localization
    mitochondrion GO:0005739 TAS
    extracellular exosome GO:0070062 IDA
    mitochondrial matrix GO:0005759 TAS
 Experiment description of studies that identified ECHS1 in exosomes
1
Experiment ID 191
ISEV standards
✘ EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ECHS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CBWD2  
Two-hybrid Homo sapiens
2 EPB41 2035
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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