Gene description for Ppic
Gene name peptidylprolyl isomerase C
Gene symbol Ppic
Other names/aliases CyP-20c
Species Mus musculus
 Database cross references - Ppic
ExoCarta ExoCarta_19038
Entrez Gene 19038
UniProt P30412  
 Ppic identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
Mov neuroglial cells 15210972    
 Gene ontology annotations for Ppic
Molecular Function
    peptidyl-prolyl cis-trans isomerase activity GO:0003755 IBA
    peptide binding GO:0042277 IEA
    isomerase activity GO:0016853 IEA
    cyclosporin A binding GO:0016018 ISO
    protein binding GO:0005515 IPI
Biological Process
    protein peptidyl-prolyl isomerization GO:0000413 IBA
    protein folding GO:0006457 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Ppic in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 39
ISEV standards
IEM
EV Biophysical techniques
TSG101|HSC70
EV Cytosolic markers
FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Ppic
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ppic is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here