Gene description for Ptgfrn |
Gene name |
prostaglandin F2 receptor negative regulator |
Gene symbol |
Ptgfrn |
Other names/aliases |
4833445A08Rik AU042434 CD9P-1 FPRP Trim45 |
Species |
Mus musculus |
Database cross references - Ptgfrn |
ExoCarta |
ExoCarta_19221 |
Entrez Gene |
19221 |
UniProt |
Q9WV91
|
Ptgfrn identified in exosomes derived from the following tissue/cell type |
Basophilic leukemia cells
|
20424270
|
Fibroblasts
|
23260141
|
Macrophages
|
23658846
|
Macrophages
|
23658846
|
Macrophages
|
23658846
|
Gene ontology annotations for Ptgfrn |
|
Experiment description of studies that identified Ptgfrn in exosomes |
1 |
Experiment ID |
89 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✔
DLS
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
20424270
|
Organism |
Rattus norvegicus |
Experiment description |
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. |
Authors |
Subra C, Grand D, Laulagnier K, Stella A, Lambeau G, Paillasse M, De Medina P, Monsarrat B, Perret B, Silvente-Poirot S, Poirot M, Record M. |
Journal name |
JLR
|
Publication year |
2010 |
Sample |
Basophilic leukemia cells |
Sample name |
RBL-2H3 |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein Lipids |
Methods used in the study |
Western blotting Gas chromatography Thin layer chromatography Mass spectrometry [Qstar XL] FACS |
|
|
2 |
Experiment ID |
210 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
CD81|FLOT1
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23260141
|
Organism |
Mus musculus |
Experiment description |
Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. |
Authors |
Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL. |
Journal name |
Cell
|
Publication year |
2012 |
Sample |
Fibroblasts |
Sample name |
Normal-Fibroblasts (L cells) |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
3 |
Experiment ID |
214 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23658846
|
Organism |
Mus musculus |
Experiment description |
Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. |
Authors |
Hassani K, Olivier M. |
Journal name |
PLoS Negl Trop Dis
|
Publication year |
2013 |
Sample |
Macrophages |
Sample name |
Leishmania-infected-Macrophage (J774A.1) |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation |
Flotation density |
1.13-1.19 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
4 |
Experiment ID |
215 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23658846
|
Organism |
Mus musculus |
Experiment description |
Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. |
Authors |
Hassani K, Olivier M. |
Journal name |
PLoS Negl Trop Dis
|
Publication year |
2013 |
Sample |
Macrophages |
Sample name |
LPS-treated-Macrophage (J774A.1) |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation |
Flotation density |
1.13-1.19 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
5 |
Experiment ID |
216 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23658846
|
Organism |
Mus musculus |
Experiment description |
Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. |
Authors |
Hassani K, Olivier M. |
Journal name |
PLoS Negl Trop Dis
|
Publication year |
2013 |
Sample |
Macrophages |
Sample name |
Normal-Macrophage (J774A.1) |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation |
Flotation density |
1.13-1.19 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for Ptgfrn |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which Ptgfrn is involved |
No pathways found
|
|
|