Gene description for Akr1d1
Gene name aldo-keto reductase family 1, member D1
Gene symbol Akr1d1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Akr1d1
ExoCarta ExoCarta_192242
Vesiclepedia VP_192242
Entrez Gene 192242
UniProt P31210  
 Akr1d1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Akr1d1
Molecular Function
    3-oxo-5-beta-steroid 4-dehydrogenase activity GO:0047568 IDA
    delta4-3-oxosteroid 5beta-reductase activity GO:0047787 IEA
    oxidoreductase activity GO:0016491 IEA
Biological Process
    C21-steroid hormone metabolic process GO:0008207 ISO
    bile acid biosynthetic process GO:0006699 ISO
    androgen metabolic process GO:0008209 ISO
    bile acid catabolic process GO:0030573 IEA
    digestion GO:0007586 ISO
    cholesterol catabolic process GO:0006707 ISO
    oxidation-reduction process GO:0055114 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytosol GO:0005829 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Akr1d1 in exosomes
1
Experiment ID 35
MISEV standards
CEM
EV Biophysical techniques
TSG101|Alix|CD81|CD63
EV Enriched markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Akr1d1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Akr1d1 is involved
No pathways found





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