Gene description for Gmpr2
Gene name guanosine monophosphate reductase 2
Gene symbol Gmpr2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gmpr2
ExoCarta ExoCarta_192357
Vesiclepedia VP_192357
Entrez Gene 192357
 Gmpr2 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gmpr2
Molecular Function
    GMP reductase activity GO:0003920 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    purine nucleobase metabolic process GO:0006144 IEA
    GMP metabolic process GO:0046037 ISO
Subcellular Localization
    GMP reductase complex GO:1902560 IEA
 Experiment description of studies that identified Gmpr2 in sEVs
1
Experiment ID 95
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gmpr2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gmpr2 is involved
No pathways found





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