Gene description for Pvrl2
Gene name	poliovirus receptor-related 2
Gene symbol	Pvrl2
Other names/aliases	AI325026 AI987993 Cd112 MPH Pvr Pvs nectin-2
Species	Mus musculus
Database cross references - Pvrl2
ExoCarta	ExoCarta_19294
Vesiclepedia	VP_19294
Entrez Gene	19294
UniProt	P32507
Pvrl2 identified in sEVs derived from the following tissue/cell type
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415

Gene ontology annotations for Pvrl2

Molecular Function     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IPI     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 IPI     protein homodimerization activity GO:0042803 ISO     cell adhesion molecule binding GO:0050839 IBA     cell adhesion molecule binding GO:0050839 IPI     cell adhesion molecule binding GO:0050839 ISO Biological Process     acrosome assembly GO:0001675 IBA     acrosome assembly GO:0001675 IMP     positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 IBA     positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 IEA     positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 ISO     positive regulation of immunoglobulin mediated immune response GO:0002891 IBA     positive regulation of immunoglobulin mediated immune response GO:0002891 IEA     positive regulation of immunoglobulin mediated immune response GO:0002891 ISO     cytoskeleton organization GO:0007010 IMP     homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IBA     homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IDA     homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 ISO     spermatid development GO:0007286 IMP     spermatid development GO:0007286 IMP     spermatid nucleus differentiation GO:0007289 IMP     fertilization GO:0009566 IMP     fusion of virus membrane with host plasma membrane GO:0019064 IEA     fusion of virus membrane with host plasma membrane GO:0019064 ISO     sperm mitochondrion organization GO:0030382 IMP     cellular anatomical entity morphogenesis GO:0032989 IMP     positive regulation of mast cell activation GO:0033005 IBA     positive regulation of mast cell activation GO:0033005 IEA     positive regulation of mast cell activation GO:0033005 ISO     susceptibility to natural killer cell mediated cytotoxicity GO:0042271 IEA     susceptibility to natural killer cell mediated cytotoxicity GO:0042271 ISO     adhesion of symbiont to host GO:0044406 ISO     cilium organization GO:0044782 IMP     positive regulation of natural killer cell mediated cytotoxicity GO:0045954 ISO     regulation of viral entry into host cell GO:0046596 IEA     regulation of viral entry into host cell GO:0046596 ISO     coreceptor-mediated virion attachment to host cell GO:0046814 IBA     coreceptor-mediated virion attachment to host cell GO:0046814 IEA     coreceptor-mediated virion attachment to host cell GO:0046814 ISO     positive regulation of T cell receptor signaling pathway GO:0050862 IBA     positive regulation of T cell receptor signaling pathway GO:0050862 IEA     positive regulation of T cell receptor signaling pathway GO:0050862 ISO     establishment of localization in cell GO:0051649 IMP     establishment of mitochondrion localization GO:0051654 IMP     susceptibility to T cell mediated cytotoxicity GO:0060370 IEA     susceptibility to T cell mediated cytotoxicity GO:0060370 ISO Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     cell-cell junction GO:0005911 IDA     cell-cell junction GO:0005911 ISO     zonula adherens GO:0005915 IDA     cell surface GO:0009986 IEA     cell surface GO:0009986 ISO     membrane GO:0016020 ISO     apical junction complex GO:0043296 IBA     apical junction complex GO:0043296 IDA     cell-cell contact zone GO:0044291 IDA