Gene description for Zzef1
Gene name zinc finger, ZZ-type with EF hand domain 1
Gene symbol Zzef1
Other names/aliases 8430405D05Rik
BC051585
C130099L13Rik
C85424
mKIAA0399
Species Mus musculus
 Database cross references - Zzef1
ExoCarta ExoCarta_195018
Vesiclepedia VP_195018
Entrez Gene 195018
UniProt Q5SSH7  
 Zzef1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zzef1
Molecular Function
    calcium ion binding GO:0005509 IEA
    zinc ion binding GO:0008270 IEA
    methylated histone binding GO:0035064 ISO
    methylated histone binding GO:0035064 ISS
    ubiquitin-like protein ligase activity GO:0061659 IMP
    lysine-acetylated histone binding GO:0070577 ISO
    lysine-acetylated histone binding GO:0070577 ISS
    histone reader activity GO:0140566 ISO
    histone reader activity GO:0140566 ISS
Biological Process
    chromatin organization GO:0006325 IEA
    neuroblast proliferation GO:0007405 IMP
    visual learning GO:0008542 IMP
    protein ubiquitination GO:0016567 IMP
    synaptic transmission, glutamatergic GO:0035249 IMP
    regulation of synaptic plasticity GO:0048167 IMP
    regulation of peptidyl-tyrosine phosphorylation GO:0050730 IMP
Subcellular Localization
    cell surface GO:0009986 IDA
    synapse GO:0045202 IDA
    presynaptic active zone GO:0048786 IDA
    postsynapse GO:0098794 IDA
 Experiment description of studies that identified Zzef1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zzef1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Zzef1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here