Gene description for SLC5A9
Gene name solute carrier family 5 (sodium/sugar cotransporter), member 9
Gene symbol SLC5A9
Other names/aliases SGLT4
Species Homo sapiens
 Database cross references - SLC5A9
ExoCarta ExoCarta_200010
Vesiclepedia VP_200010
Entrez Gene 200010
HGNC 22146
UniProt Q2M3M2  
 SLC5A9 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SLC5A9
Molecular Function
    low-affinity D-glucose:sodium symporter activity GO:0005362 TAS
    D-glucose:sodium symporter activity GO:0005412 IBA
Biological Process
    hexose transmembrane transport GO:0008645 TAS
    sodium ion transmembrane transport GO:0035725 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SLC5A9 in sEVs
1
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SLC5A9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD63 967
Affinity Capture-MS Homo sapiens
2 GIF  
Affinity Capture-MS Homo sapiens
3 KLF8  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SLC5A9 is involved
PathwayEvidenceSource
Cellular hexose transport TAS Reactome
SLC-mediated transmembrane transport TAS Reactome
Transport of small molecules TAS Reactome





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