Gene description for Rras
Gene name Harvey rat sarcoma oncogene, subgroup R
Gene symbol Rras
Other names/aliases AI573426
Species Mus musculus
 Database cross references - Rras
ExoCarta ExoCarta_20130
Entrez Gene 20130
UniProt P10833  
 Rras identified in exosomes derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Rras
Molecular Function
    GDP binding GO:0019003 ISO
    GTP binding GO:0005525 IEA
    nucleotide binding GO:0000166 IEA
    GTPase activity GO:0003924 ISO
    protein complex binding GO:0032403 ISO
Biological Process
    signal transduction GO:0007165 IEA
    negative regulation of cell migration GO:0030336 IGI
    regulation of ERK1 and ERK2 cascade GO:0070372 ISO
    face morphogenesis GO:0060325 ISO
    positive regulation of angiogenesis GO:0045766 ISO
    regulation of protein kinase B signaling GO:0051896 ISO
    small GTPase mediated signal transduction GO:0007264 IEA
    leukocyte differentiation GO:0002521 ISO
    metabolic process GO:0008152 ISO
Subcellular Localization
    plasma membrane GO:0005886 IEA
    membrane GO:0016020 IEA
    extracellular exosome GO:0070062 ISO
    focal adhesion GO:0005925 ISO
 Experiment description of studies that identified Rras in exosomes
1
Experiment ID 39
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG101|HSC70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Rras
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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