Experiment description of studies that identified Apcs in sEVs

1 Experiment ID 303 MISEV standards ✔ EM Biophysical techniques ✔ Cd63|Cd81|Cd9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33431899     Organism Mus musculus Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." Journal name Nat Commun Publication year 2021 Sample Faeces Sample name Intestinal epithelial cells - C57BL/6 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation Flotation density - Molecules identified in the study Protein Lipid miRNA Methods used in the study Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC

2 Experiment ID 304 MISEV standards ✔ EM Biophysical techniques ✔ Cd63|Cd81|Cd9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33431899     Organism Mus musculus Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." Journal name Nat Commun Publication year 2021 Sample Faeces Sample name Intestinal epithelial cells - C57BL/6 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation Flotation density - Molecules identified in the study Protein Lipid miRNA Methods used in the study Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC

Protein-protein interactions for Apcs

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Fancd2   Affinity Capture-MS Mus musculus 2 Lama1   Co-fractionation Mus musculus 3 Tg 21819 Co-fractionation Mus musculus View the network

Pathways in which Apcs is involved

No pathways found