Gene description for Slbp
Gene name stem-loop binding protein
Gene symbol Slbp
Other names/aliases -
Species Mus musculus
 Database cross references - Slbp
ExoCarta ExoCarta_20492
Vesiclepedia VP_20492
Entrez Gene 20492
UniProt P97440  
 Slbp identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Slbp
Molecular Function
    mRNA binding GO:0003729 IBA
    mRNA binding GO:0003729 IDA
    mRNA binding GO:0003729 ISO
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    histone pre-mRNA stem-loop binding GO:0071207 IBA
    histone pre-mRNA stem-loop binding GO:0071207 IDA
Biological Process
    cap-dependent translational initiation GO:0002191 ISO
    mRNA 3'-end processing by stem-loop binding and cleavage GO:0006398 IBA
    mRNA 3'-end processing by stem-loop binding and cleavage GO:0006398 IDA
    mRNA transport GO:0051028 IBA
    mRNA transport GO:0051028 ISO
    mRNA transport GO:0051028 ISS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 IEA
    nucleolus GO:0005730 ISO
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    histone mRNA stem-loop binding complex GO:0062073 ISO
    histone pre-mRNA 3'end processing complex GO:0071204 IBA
    histone pre-mRNA 3'end processing complex GO:0071204 IDA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified Slbp in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Slbp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here