Gene description for Slbp
Gene name stem-loop binding protein
Gene symbol Slbp
Other names/aliases -
Species Mus musculus
 Database cross references - Slbp
ExoCarta ExoCarta_20492
Entrez Gene 20492
UniProt P97440  
 Slbp identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Slbp
Molecular Function
    mRNA binding GO:0003729 ISO
    RNA binding GO:0003723 IEA
    histone pre-mRNA stem-loop binding GO:0071207 IDA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    histone mRNA 3'-end processing GO:0006398 IDA
    nuclear DNA replication GO:0033260 ISO
    mRNA transport GO:0051028 ISO
    mRNA processing GO:0006397 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 ISO
    ribonucleoprotein complex GO:0030529 IDA
    histone pre-mRNA 3'end processing complex GO:0071204 IDA
 Experiment description of studies that identified Slbp in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Slbp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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