Gene description for Slc1a5
Gene name solute carrier family 1 (neutral amino acid transporter), member 5
Gene symbol Slc1a5
Other names/aliases AAAT
Species Mus musculus
 Database cross references - Slc1a5
ExoCarta ExoCarta_20514
Entrez Gene 20514
 Slc1a5 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Slc1a5
Molecular Function
    L-serine transmembrane transporter activity GO:0015194 ISO
    neutral amino acid transmembrane transporter activity GO:0015175 IDA
    sodium:dicarboxylate symporter activity GO:0017153 IEA
    symporter activity GO:0015293 IEA
    amino acid transmembrane transporter activity GO:0015171 ISO
Biological Process
    L-serine transport GO:0015825 ISO
    amino acid transmembrane transport GO:0003333 ISO
    extracellular amino acid transport GO:0006860 ISO
    dicarboxylic acid transport GO:0006835 IEA
    transport GO:0006810 IEA
    L-alpha-amino acid transmembrane transport GO:1902475 ISO
    cation transmembrane transport GO:0098655 ISO
    neutral amino acid transport GO:0015804 IDA
Subcellular Localization
    plasma membrane GO:0005886 ISO
    Golgi apparatus GO:0005794 ISO
    membrane GO:0016020 ISO
    integral component of membrane GO:0016021 IEA
    extracellular exosome GO:0070062 ISO
    extracellular region GO:0005576 ISO
 Experiment description of studies that identified Slc1a5 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Slc1a5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc1a5 is involved
No pathways found

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