Gene description for Sox6
Gene name	SRY (sex determining region Y)-box 6
Gene symbol	Sox6
Other names/aliases	AI987981 SOX-LZ
Species	Mus musculus
Database cross references - Sox6
ExoCarta	ExoCarta_20679
Vesiclepedia	VP_20679
Entrez Gene	20679
UniProt	P40645
Sox6 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Sox6

Molecular Function     transcription cis-regulatory region binding GO:0000976 IDA     transcription cis-regulatory region binding GO:0000976 ISO     transcription cis-regulatory region binding GO:0000976 ISS     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IMP     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     cis-regulatory region sequence-specific DNA binding GO:0000987 ISO     DNA-binding transcription repressor activity GO:0001217 IDA     DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IMP     DNA binding GO:0003677 IDA     DNA-binding transcription factor activity GO:0003700 IDA     DNA-binding transcription factor activity GO:0003700 IGI     DNA-binding transcription factor activity GO:0003700 ISO     protein binding GO:0005515 IPI     protein homodimerization activity GO:0042803 ISO     protein homodimerization activity GO:0042803 ISS     sequence-specific DNA binding GO:0043565 IDA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     negative regulation of transcription by RNA polymerase II GO:0000122 IMP     negative regulation of transcription by RNA polymerase II GO:0000122 IMP     cell morphogenesis GO:0000902 IMP     cartilage condensation GO:0001502 IMP     in utero embryonic development GO:0001701 IMP     chondrocyte differentiation GO:0002062 IMP     regulation of DNA-templated transcription GO:0006355 IDA     regulation of transcription by RNA polymerase II GO:0006357 IBA     central nervous system development GO:0007417 IBA     brain development GO:0007420 ISO     brain development GO:0007420 ISS     post-embryonic development GO:0009791 IMP     gene expression GO:0010467 IMP     regulation of gene expression GO:0010468 IMP     spinal cord oligodendrocyte cell differentiation GO:0021529 IMP     oligodendrocyte cell fate specification GO:0021778 IMP     hemopoiesis GO:0030097 IMP     erythrocyte differentiation GO:0030218 IMP     positive regulation of chondrocyte differentiation GO:0032332 IBA     positive regulation of chondrocyte differentiation GO:0032332 IDA     positive regulation of chondrocyte differentiation GO:0032332 ISO     cell fate commitment GO:0045165 IBA     cell fate commitment GO:0045165 IGI     negative regulation of DNA-templated transcription GO:0045892 IDA     negative regulation of DNA-templated transcription GO:0045892 IMP     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IGI     astrocyte differentiation GO:0048708 ISO     oligodendrocyte differentiation GO:0048709 IMP     erythrocyte development GO:0048821 IMP     regulation of DNA-binding transcription factor activity GO:0051090 IMP     cartilage development GO:0051216 IDA     cartilage development GO:0051216 IGI     cartilage development GO:0051216 IMP     cardiac muscle cell differentiation GO:0055007 IDA     positive regulation of cartilage development GO:0061036 ISO     cellular response to transforming growth factor beta stimulus GO:0071560 ISO     negative regulation of cardiac muscle cell differentiation GO:2000726 ISO     positive regulation of mesenchymal stem cell differentiation GO:2000741 ISO Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IC     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     transcription regulator complex GO:0005667 IC     cytoplasm GO:0005737 IEA