Gene description for Rbms3
Gene name RNA binding motif, single stranded interacting protein
Gene symbol Rbms3
Other names/aliases 6720477E09Rik
8430436O14Rik
Species Mus musculus
 Database cross references - Rbms3
ExoCarta ExoCarta_207181
Vesiclepedia VP_207181
Entrez Gene 207181
UniProt Q8BWL5  
 Rbms3 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rbms3
Molecular Function
    mRNA 3'-UTR binding GO:0003730 IBA
    mRNA 3'-UTR binding GO:0003730 IDA
    poly(A) binding GO:0008143 IBA
    poly(A) binding GO:0008143 ISO
    poly(U) RNA binding GO:0008266 IBA
    poly(U) RNA binding GO:0008266 ISO
    mRNA 3'-UTR AU-rich region binding GO:0035925 ISO
Biological Process
    defense response to tumor cell GO:0002357 ISO
    positive regulation of gene expression GO:0010628 ISO
    negative regulation of gene expression GO:0010629 ISO
    positive regulation of translation GO:0045727 IDA
    negative regulation of canonical Wnt signaling pathway GO:0090090 ISO
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IBA
    ribonucleoprotein complex GO:1990904 IBA
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified Rbms3 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rbms3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rbms3 is involved
No pathways found





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