Gene description for Spn
Gene name	sialophorin
Gene symbol	Spn
Other names/aliases	A630014B01Rik Cd43 Galgp Ly-48 Ly48
Species	Mus musculus
Database cross references - Spn
ExoCarta	ExoCarta_20737
Entrez Gene	20737
UniProt	P15702
Spn identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846
Mast cells	17486113

Gene ontology annotations for Spn

Molecular Function     protein binding GO:0005515 IPI     protein domain specific binding GO:0019904 ISO Biological Process     negative regulation of T cell proliferation GO:0042130 IMP     apoptotic signaling pathway GO:0097190 IDA     negative regulation of T cell activation GO:0050868 IMP     positive regulation of tumor necrosis factor biosynthetic process GO:0042535 ISO     T cell costimulation GO:0031295 IDA     regulation of defense response to virus GO:0050688 IMP     negative regulation of cell adhesion GO:0007162 IMP     defense response to bacterium GO:0042742 ISO     negative thymic T cell selection GO:0045060 IMP     positive regulation of T cell proliferation GO:0042102 IDA     thymocyte aggregation GO:0071594 ISO     response to protozoan GO:0001562 IDA     regulation of immune response GO:0050776 IMP     cell surface receptor signaling pathway GO:0007166 IDA     positive regulation of protein phosphorylation GO:0001934 IGI     negative regulation of type IV hypersensitivity GO:0001808 IMP Subcellular Localization     cleavage furrow GO:0032154 ISO     external side of plasma membrane GO:0009897 IDA     integral component of plasma membrane GO:0005887 IDA     cell surface GO:0009986 ISO     extracellular space GO:0005615 ISO     microvillus GO:0005902 ISO     uropod GO:0001931 IDA     integral component of membrane GO:0016021 IEA     membrane GO:0016020 ISO     extracellular exosome GO:0070062 ISO     basement membrane GO:0005604 IDA