Gene description for Spp1
Gene name	secreted phosphoprotein 1
Gene symbol	Spp1
Other names/aliases	2AR Apl-1 BNSP BSPI Bsp ETA-1 Eta OP Opn Opnl Ric Spp-1
Species	Mus musculus
Database cross references - Spp1
ExoCarta	ExoCarta_20750
Entrez Gene	20750
UniProt	P10923
Spp1 identified in exosomes derived from the following tissue/cell type
Fibroblasts	23260141

Gene ontology annotations for Spp1

Molecular Function     extracellular matrix binding GO:0050840 IDA     cytokine activity GO:0005125 NAS Biological Process     response to organic substance GO:0010033 ISO     biomineral tissue development GO:0031214 IEA     cellular response to fluid shear stress GO:0071498 IDA     cell adhesion GO:0007155 ISO     response to vitamin D GO:0033280 ISO     positive regulation of cell-substrate adhesion GO:0010811 IDA     ossification GO:0001503 IEA     response to steroid hormone GO:0048545 ISO     negative regulation of apoptotic process GO:0043066 NAS     positive regulation of bone resorption GO:0045780 ISO     osteoblast differentiation GO:0001649 ISO     neutrophil chemotaxis GO:0030593 IGI Subcellular Localization     extracellular exosome GO:0070062 ISO     extracellular space GO:0005615 ISO     apical part of cell GO:0045177 IDA     perinuclear region of cytoplasm GO:0048471 ISO     extracellular region GO:0005576 NAS     membrane-bounded vesicle GO:0031988 ISO     cell projection GO:0042995 ISO     cytoplasm GO:0005737 IDA