Gene description for Camkk2
Gene name calcium/calmodulin-dependent protein kinase kinase 2, beta
Gene symbol Camkk2
Other names/aliases 6330570N16Rik
AW061083
mKIAA0787
Species Mus musculus
 Database cross references - Camkk2
ExoCarta ExoCarta_207565
Entrez Gene 207565
UniProt Q8C078  
 Camkk2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Camkk2
Molecular Function
    protein serine/threonine kinase activity GO:0004674 IEA
    calcium ion binding GO:0005509 ISO
    transferase activity, transferring phosphorus-containing groups GO:0016772 IEA
    calmodulin-dependent protein kinase activity GO:0004683 ISO
    nucleotide binding GO:0000166 IEA
    kinase activity GO:0016301 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    protein kinase activity GO:0004672 IEA
    calmodulin binding GO:0005516 ISO
    transferase activity GO:0016740 IEA
Biological Process
    protein autophosphorylation GO:0046777 ISO
    phosphorylation GO:0016310 IEA
    activation of protein kinase activity GO:0032147 ISO
    protein phosphorylation GO:0006468 ISO
Subcellular Localization
    cell projection GO:0042995 IEA
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Camkk2 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Camkk2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Camkk2 is involved
No pathways found





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