Gene description for Sephs2
Gene name selenophosphate synthetase 2
Gene symbol Sephs2
Other names/aliases Sps2
Ysg3
Species Mus musculus
 Database cross references - Sephs2
ExoCarta ExoCarta_20768
Vesiclepedia VP_20768
Entrez Gene 20768
UniProt P97364  
 Sephs2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Sephs2
Molecular Function
    selenide, water dikinase activity GO:0004756 IBA
    selenide, water dikinase activity GO:0004756 IDA
    ATP binding GO:0005524 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    selenium compound metabolic process GO:0001887 IDA
    selenium compound metabolic process GO:0001887 IMP
    selenocysteine biosynthetic process GO:0016260 IBA
    selenocysteine biosynthetic process GO:0016260 IMP
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified Sephs2 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Sephs2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Sephs1  
Co-fractionation Mus musculus
View the network image/svg+xml



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