Gene description for Sephs2
Gene name selenophosphate synthetase 2
Gene symbol Sephs2
Other names/aliases Sps2
Ysg3
Species Mus musculus
 Database cross references - Sephs2
ExoCarta ExoCarta_20768
Entrez Gene 20768
UniProt P97364  
 Sephs2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Sephs2
Molecular Function
    catalytic activity GO:0003824 IEA
    ATP binding GO:0005524 IEA
    nucleotide binding GO:0000166 IEA
    kinase activity GO:0016301 IEA
    transferase activity GO:0016740 IEA
    selenide, water dikinase activity GO:0004756 IDA
Biological Process
    selenium compound metabolic process GO:0001887 IMP
    phosphorylation GO:0016310 IDA
    selenocysteine biosynthetic process GO:0016260 IMP
 Experiment description of studies that identified Sephs2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Sephs2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sephs2 is involved
No pathways found





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