Gene description for Ssrp1
Gene name structure specific recognition protein 1
Gene symbol Ssrp1
Other names/aliases C81323
Hmg1-rs1
Hmgi-rs3
Hmgox
T160
Species Mus musculus
 Database cross references - Ssrp1
ExoCarta ExoCarta_20833
Vesiclepedia VP_20833
Entrez Gene 20833
UniProt Q08943  
 Ssrp1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ssrp1
Molecular Function
    DNA binding GO:0003677 IEA
    chromatin binding GO:0003682 IDA
    nucleosome binding GO:0031491 IBA
    histone binding GO:0042393 IBA
Biological Process
    DNA replication GO:0006260 IEA
    DNA repair GO:0006281 IEA
    nucleosome assembly GO:0006334 NAS
    nucleosome disassembly GO:0006337 ISO
    regulation of chromatin organization GO:1902275 IBA
    regulation of chromatin organization GO:1902275 IEA
    regulation of chromatin organization GO:1902275 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleolus GO:0005730 IEA
    FACT complex GO:0035101 IBA
    FACT complex GO:0035101 ISO
 Experiment description of studies that identified Ssrp1 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ssrp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fancd2  
Affinity Capture-MS Mus musculus
2 Nanog  
Affinity Capture-MS Mus musculus
3 Eed  
Affinity Capture-MS Mus musculus
4 Tmem173  
Proximity Label-MS Mus musculus
5 Pou5f1  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
Co-fractionation Mus musculus
View the network image/svg+xml



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