Gene description for Ttc28
Gene name tetratricopeptide repeat domain 28
Gene symbol Ttc28
Other names/aliases 2310015L07Rik
6030435N04
AI428795
AI851761
BC002262
TPRBK
Species Mus musculus
 Database cross references - Ttc28
ExoCarta ExoCarta_209683
Entrez Gene 209683
UniProt Q80XJ3  
 Ttc28 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ttc28
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    cell division GO:0051301 IEA
    cell cycle GO:0007049 IEA
    regulation of mitotic cell cycle GO:0007346 ISO
    mitotic nuclear division GO:0007067 IEA
Subcellular Localization
    mitotic spindle midzone GO:1990023 ISO
    mitotic spindle GO:0072686 ISO
    cytoplasm GO:0005737 IEA
    centrosome GO:0005813 ISO
    midbody GO:0030496 ISO
    mitotic spindle pole GO:0097431 ISO
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified Ttc28 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ttc28
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ttc28 is involved
No pathways found





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