Gene description for Sdc1
Gene name syndecan 1
Gene symbol Sdc1
Other names/aliases AA408134
Species Mus musculus
 Database cross references - Sdc1
ExoCarta ExoCarta_20969
Entrez Gene 20969
UniProt P18828  
 Sdc1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Sdc1
Molecular Function
    glycoprotein binding GO:0001948 IPI
    protein C-terminus binding GO:0008022 ISO
Biological Process
    myoblast development GO:0048627 IDA
    inflammatory response GO:0006954 ISO
    positive regulation of exosomal secretion GO:1903543 ISO
    cell migration GO:0016477 IBA
    canonical Wnt signaling pathway GO:0060070 IMP
    positive regulation of extracellular exosome assembly GO:1903553 ISO
Subcellular Localization
    external side of plasma membrane GO:0009897 IDA
    integral component of membrane GO:0016021 IEA
    extracellular region GO:0005576 IEA
    protein complex GO:0043234 ISO
    extracellular exosome GO:0070062 ISO
    focal adhesion GO:0005925 ISO
    cell surface GO:0009986 ISO
    membrane GO:0016020 IEA
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Sdc1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Sdc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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