Gene description for Sdc1
Gene name syndecan 1
Gene symbol Sdc1
Other names/aliases AA408134
AA409076
CD138
Sstn
Synd
Synd1
syn-1
Species Mus musculus
 Database cross references - Sdc1
ExoCarta ExoCarta_20969
Vesiclepedia VP_20969
Entrez Gene 20969
UniProt P18828  
 Sdc1 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Sdc1
Molecular Function
    protein binding GO:0005515 IPI
    cargo receptor activity GO:0038024 IMP
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
Biological Process
    ureteric bud development GO:0001657 IEA
    receptor-mediated endocytosis GO:0006898 IMP
    response to toxic substance GO:0009636 IEA
    cell migration GO:0016477 IBA
    response to hydrogen peroxide GO:0042542 IEA
    myoblast development GO:0048627 IDA
    response to glucocorticoid GO:0051384 IEA
    response to cAMP GO:0051591 IEA
    response to calcium ion GO:0051592 IEA
    striated muscle cell development GO:0055002 IEA
    Sertoli cell development GO:0060009 IEA
    canonical Wnt signaling pathway GO:0060070 IMP
    positive regulation of exosomal secretion GO:1903543 IEA
    positive regulation of exosomal secretion GO:1903543 ISO
    positive regulation of extracellular exosome assembly GO:1903553 IEA
    positive regulation of extracellular exosome assembly GO:1903553 ISO
Subcellular Localization
    extracellular region GO:0005576 TAS
    Golgi lumen GO:0005796 TAS
    plasma membrane GO:0005886 IMP
    external side of plasma membrane GO:0009897 IDA
    cell surface GO:0009986 IBA
    cell surface GO:0009986 IDA
    cell surface GO:0009986 ISO
    protein-containing complex GO:0032991 IEA
    protein-containing complex GO:0032991 ISO
 Experiment description of studies that identified Sdc1 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Sdc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Atg5  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here