Gene description for Papd7
Gene name PAP associated domain containing 7
Gene symbol Papd7
Other names/aliases LAK-1
POLK
Pols
TRF4
TRF4-1
Species Mus musculus
 Database cross references - Papd7
ExoCarta ExoCarta_210106
Entrez Gene 210106
UniProt Q6PB75  
 Papd7 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Papd7
Molecular Function
    metal ion binding GO:0046872 IEA
    DNA binding GO:0003677 IEA
    polynucleotide adenylyltransferase activity GO:0004652 IEA
    nucleotidyltransferase activity GO:0016779 IEA
    molecular_function GO:0003674 ND
    transferase activity GO:0016740 IEA
    DNA-directed DNA polymerase activity GO:0003887 IEA
Biological Process
    DNA biosynthetic process GO:0071897 IEA
    cell cycle GO:0007049 IEA
    mitotic nuclear division GO:0007067 IEA
    response to drug GO:0042493 ISO
    cell division GO:0051301 IEA
Subcellular Localization
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Papd7 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Papd7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Papd7 is involved
No pathways found





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