Gene description for Lpp
Gene name LIM domain containing preferred translocation partner in lipoma
Gene symbol Lpp
Other names/aliases 9430020K16Rik
AA959454
AU024130
B130055L10Rik
C79715
D630048H16
Species Mus musculus
 Database cross references - Lpp
ExoCarta ExoCarta_210126
Vesiclepedia VP_210126
Entrez Gene 210126
UniProt Q8BFW7  
 Lpp identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Lpp
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    cell adhesion GO:0007155 IEA
    cell-cell adhesion GO:0098609 IBA
Subcellular Localization
    stress fiber GO:0001725 IBA
    nucleus GO:0005634 IEA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    focal adhesion GO:0005925 IBA
    focal adhesion GO:0005925 IEA
    focal adhesion GO:0005925 ISO
 Experiment description of studies that identified Lpp in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Lpp
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Iqcb1  
Affinity Capture-MS Mus musculus
2 Fancd2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Lpp is involved
No pathways found





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