Gene description for Nomo1
Gene name nodal modulator 1
Gene symbol Nomo1
Other names/aliases D7Ertd156e
Nomo
pM5
Species Mus musculus
 Database cross references - Nomo1
ExoCarta ExoCarta_211548
Vesiclepedia VP_211548
Entrez Gene 211548
UniProt Q6GQT9  
 Nomo1 identified in sEVs derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Nomo1
Molecular Function
    molecular_function GO:0003674 ND
    carbohydrate binding GO:0030246 IEA
    ribosome binding GO:0043022 ISO
    ribosome binding GO:0043022 ISS
Biological Process
    biological_process GO:0008150 ND
    multi-pass transmembrane protein insertion into ER membrane GO:0160063 ISS
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IEA
    endoplasmic reticulum membrane GO:0005789 ISO
    protein-containing complex GO:0032991 ISO
    multi-pass translocon complex GO:0160064 ISO
    multi-pass translocon complex GO:0160064 ISS
 Experiment description of studies that identified Nomo1 in sEVs
1
Experiment ID 264
MISEV standards
Biophysical techniques
CD63|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Nomo1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Lnx2  
Affinity Capture-MS Mus musculus
2 Lipc  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Nomo1 is involved
No pathways found





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