Gene description for Asap2
Gene name ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Gene symbol Asap2
Other names/aliases 6530401G17Rik
Ddef2
Gm1523
Gm592
PAG3
PAP
Species Mus musculus
 Database cross references - Asap2
ExoCarta ExoCarta_211914
Vesiclepedia VP_211914
Entrez Gene 211914
UniProt Q7SIG6  
 Asap2 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Asap2
Molecular Function
    GTPase activator activity GO:0005096 IBA
    GTPase activator activity GO:0005096 IEA
    metal ion binding GO:0046872 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
    cytosol GO:0005829 ISO
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    Golgi cisterna membrane GO:0032580 IEA
 Experiment description of studies that identified Asap2 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Asap2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Vill  
Co-fractionation Mus musculus
2 Kcna3  
Affinity Capture-MS Mus musculus
3 Sharpin  
Affinity Capture-MS Mus musculus
4 Syngap1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Asap2 is involved
No pathways found





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