Gene description for Tagln2
Gene name transgelin 2
Gene symbol Tagln2
Other names/aliases 2700094C18Rik
SM22beta
Sm22B
Sm22a
Species Mus musculus
 Database cross references - Tagln2
ExoCarta ExoCarta_21346
Entrez Gene 21346
UniProt Q9WVA4  
 Tagln2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tagln2
Molecular Function
    actin filament binding GO:0051015 IEA
Biological Process
    epithelial cell differentiation GO:0030855 ISO
Subcellular Localization
    vesicle GO:0031982 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Tagln2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tagln2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tagln2 is involved
No pathways found





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