Gene description for Ago3
Gene name	argonaute RISC catalytic subunit 3
Gene symbol	Ago3
Other names/aliases	AW048688 C130014L07Rik Eif2c3
Species	Mus musculus
Database cross references - Ago3
ExoCarta	ExoCarta_214150
Vesiclepedia	VP_214150
Entrez Gene	214150
UniProt	Q8CJF9
Ago3 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Ago3

Molecular Function     RNA binding GO:0003723 IDA     double-stranded RNA binding GO:0003725 IEA     double-stranded RNA binding GO:0003725 ISO     single-stranded RNA binding GO:0003727 IBA     single-stranded RNA binding GO:0003727 IEA     single-stranded RNA binding GO:0003727 ISO     RNA endonuclease activity GO:0004521 IBA     RNA endonuclease activity GO:0004521 ISO     RNA endonuclease activity GO:0004521 ISS     miRNA binding GO:0035198 IBA     miRNA binding GO:0035198 IEA     miRNA binding GO:0035198 ISO     metal ion binding GO:0046872 IEA     endoribonuclease activity, cleaving miRNA-paired mRNA GO:0090624 ISO     endoribonuclease activity, cleaving miRNA-paired mRNA GO:0090624 ISS Biological Process     mRNA catabolic process GO:0006402 ISO     mRNA catabolic process GO:0006402 ISS     RNA secondary structure unwinding GO:0010501 IEA     RNA secondary structure unwinding GO:0010501 ISO     positive regulation of gene expression GO:0010628 IMP     pre-miRNA processing GO:0031054 IBA     pre-miRNA processing GO:0031054 IEA     pre-miRNA processing GO:0031054 ISO     regulatory ncRNA-mediated post-transcriptional gene silencing GO:0035194 IBA     miRNA processing GO:0035196 ISO     miRNA-mediated gene silencing by inhibition of translation GO:0035278 ISO     miRNA-mediated gene silencing by inhibition of translation GO:0035278 ISS     miRNA-mediated gene silencing by mRNA destabilization GO:0035279 IEA     RISC complex assembly GO:0070922 IEA     RISC complex assembly GO:0070922 ISO     regulation of stem cell proliferation GO:0072091 IEA     regulation of stem cell proliferation GO:0072091 ISO     positive regulation of non-canonical NF-kappaB signal transduction GO:1901224 IMP Subcellular Localization     condensed nuclear chromosome GO:0000794 IDA     P-body GO:0000932 IEA     nucleus GO:0005634 IBA     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     RISC complex GO:0016442 IBA     RISC complex GO:0016442 IDA     RISC complex GO:0016442 ISO     cytoplasmic ribonucleoprotein granule GO:0036464 IBA     cytoplasmic ribonucleoprotein granule GO:0036464 ISO     RISC-loading complex GO:0070578 IEA     RISC-loading complex GO:0070578 ISO