Gene description for Zcchc6
Gene name zinc finger, CCHC domain containing 6
Gene symbol Zcchc6
Other names/aliases 6030448M23Rik
AA420405
Species Mus musculus
 Database cross references - Zcchc6
ExoCarta ExoCarta_214290
Entrez Gene 214290
UniProt Q5BLK4  
 Zcchc6 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zcchc6
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    nucleotidyltransferase activity GO:0016779 IEA
    transferase activity GO:0016740 IEA
    metal ion binding GO:0046872 IEA
    RNA uridylyltransferase activity GO:0050265 ISO
    zinc ion binding GO:0008270 IEA
    nucleic acid binding GO:0003676 IEA
Biological Process
    RNA 3'-end processing GO:0031123 ISO
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Zcchc6 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zcchc6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Zcchc6 is involved
No pathways found





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