Gene description for She
Gene name src homology 2 domain-containing transforming protein E
Gene symbol She
Other names/aliases 9430022A14
Species Mus musculus
 Database cross references - She
ExoCarta ExoCarta_214547
Vesiclepedia VP_214547
Entrez Gene 214547
UniProt Q8BSD5  
 She identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for She
Molecular Function
    phosphotyrosine residue binding GO:0001784 IBA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified She in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for She
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Usp7  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which She is involved
No pathways found





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