Gene description for Nav1
Gene name neuron navigator 1
Gene symbol Nav1
Other names/aliases 9530089B19
9930003A20Rik
C230080M11Rik
Pomfil3
Unc53h1
mKIAA1151
steerin-1
Species Mus musculus
 Database cross references - Nav1
ExoCarta ExoCarta_215690
Entrez Gene 215690
UniProt Q8CH77  
 Nav1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nav1
Biological Process
    multicellular organismal development GO:0007275 IEA
    microtubule bundle formation GO:0001578 IDA
    neuron migration GO:0001764 IMP
    cell differentiation GO:0030154 IEA
    nervous system development GO:0007399 IEA
Subcellular Localization
    microtubule GO:0005874 IEA
    microtubule cytoskeleton GO:0015630 IDA
    cytoplasm GO:0005737 IEA
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified Nav1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nav1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nav1 is involved
No pathways found





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