Gene description for Rab3ip
Gene name RAB3A interacting protein
Gene symbol Rab3ip
Other names/aliases B230311A06
Gtpat12
Rabin3
Species Mus musculus
 Database cross references - Rab3ip
ExoCarta ExoCarta_216363
Entrez Gene 216363
UniProt Q68EF0  
 Rab3ip identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Rab3ip
Molecular Function
    GTPase binding GO:0051020 ISO
    Rab guanyl-nucleotide exchange factor activity GO:0017112 ISO
    guanyl-nucleotide exchange factor activity GO:0005085 IEA
Biological Process
    transport GO:0006810 IEA
    positive regulation of GTPase activity GO:0043547 ISO
    protein targeting to membrane GO:0006612 ISO
    protein transport GO:0015031 IEA
    protein localization to organelle GO:0033365 ISO
    cilium assembly GO:0042384 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    cytoskeleton GO:0005856 IEA
    centrosome GO:0005813 ISO
    cell projection GO:0042995 IEA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Rab3ip in exosomes
1
Experiment ID 264
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Rab3ip
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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