Gene description for Myl6b
Gene name myosin, light polypeptide 6B
Gene symbol Myl6b
Other names/aliases 5730437E04Rik
BC037527
MLC1SA
Species Mus musculus
 Database cross references - Myl6b
ExoCarta ExoCarta_216459
Vesiclepedia VP_216459
Entrez Gene 216459
UniProt Q8CI43  
 Myl6b identified in sEVs derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Myl6b
Molecular Function
    cytoskeletal motor activity GO:0003774 TAS
    calcium ion binding GO:0005509 IEA
    structural constituent of muscle GO:0008307 IBA
    structural constituent of muscle GO:0008307 TAS
Biological Process
    muscle contraction GO:0006936 TAS
    skeletal muscle tissue development GO:0007519 TAS
    muscle filament sliding GO:0030049 TAS
Subcellular Localization
    myosin complex GO:0016459 TAS
    myosin II complex GO:0016460 IBA
    unconventional myosin complex GO:0016461 TAS
 Experiment description of studies that identified Myl6b in sEVs
1
Experiment ID 39
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|HSC70|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors "Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G"
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Myl6b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Irf3  
Co-fractionation Mus musculus
2 Zbtb7b  
Affinity Capture-MS Mus musculus
3 Fancd2  
Affinity Capture-MS Mus musculus
4 Eif2b5  
Co-fractionation Mus musculus
5 Tssc1  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Myl6b is involved
PathwayEvidenceSource
Muscle contraction IEA Reactome
Smooth Muscle Contraction IEA Reactome





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