Gene description for Myl6b
Gene name myosin, light polypeptide 6B
Gene symbol Myl6b
Other names/aliases 5730437E04Rik
BC037527
MLC1SA
Species Mus musculus
 Database cross references - Myl6b
ExoCarta ExoCarta_216459
Entrez Gene 216459
UniProt Q8CI43  
 Myl6b identified in exosomes derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Myl6b
Molecular Function
    structural constituent of muscle GO:0008307 TAS
    motor activity GO:0003774 TAS
    calcium ion binding GO:0005509 IEA
Biological Process
    muscle filament sliding GO:0030049 TAS
    skeletal muscle tissue development GO:0007519 TAS
    muscle contraction GO:0006936 TAS
Subcellular Localization
    unconventional myosin complex GO:0016461 TAS
    myosin complex GO:0016459 TAS
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Myl6b in exosomes
1
Experiment ID 39
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG101|HSC70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Myl6b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Myl6b is involved
PathwayEvidenceSource
Smooth Muscle Contraction IEA Reactome





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