Gene description for Tgfbi
Gene name transforming growth factor, beta induced
Gene symbol Tgfbi
Other names/aliases 68kDa
AI181842
AI747162
Beta-ig
big-h3
Species Mus musculus
 Database cross references - Tgfbi
ExoCarta ExoCarta_21810
Entrez Gene 21810
UniProt P82198  
 Tgfbi identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Tgfbi
Molecular Function
    collagen binding GO:0005518 ISO
    extracellular matrix binding GO:0050840 IDA
    cell adhesion molecule binding GO:0050839 IBA
Biological Process
    cell adhesion GO:0007155 IDA
    extracellular matrix organization GO:0030198 IDA
Subcellular Localization
    extracellular matrix GO:0031012 ISO
    trans-Golgi network GO:0005802 ISO
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 ISO
    extracellular exosome GO:0070062 ISO
    proteinaceous extracellular matrix GO:0005578 IDA
    basement membrane GO:0005604 ISO
 Experiment description of studies that identified Tgfbi in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tgfbi
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tgfbi is involved
No pathways found





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