Gene description for Tnfaip1
Gene name	tumor necrosis factor, alpha-induced protein 1 (endothelial)
Gene symbol	Tnfaip1
Other names/aliases	Edp-1 Edp1 Tnfip1
Species	Mus musculus
Database cross references - Tnfaip1
ExoCarta	ExoCarta_21927
Vesiclepedia	VP_21927
Entrez Gene	21927
UniProt	O70479
Tnfaip1 identified in sEVs derived from the following tissue/cell type
Fibroblasts	23260141

Gene ontology annotations for Tnfaip1

Molecular Function     ubiquitin-protein transferase activity GO:0004842 IBA     ubiquitin-protein transferase activity GO:0004842 ISO     ubiquitin-protein transferase activity GO:0004842 ISS     cyclin binding GO:0030332 IEA     cyclin binding GO:0030332 ISO     small GTPase binding GO:0031267 ISO     small GTPase binding GO:0031267 ISS     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO Biological Process     immune response GO:0006955 ISS     cell migration GO:0016477 ISO     cell migration GO:0016477 ISS     protein ubiquitination GO:0016567 IBA     protein ubiquitination GO:0016567 IEA     protein ubiquitination GO:0016567 ISO     protein ubiquitination GO:0016567 ISS     negative regulation of Rho protein signal transduction GO:0035024 IBA     negative regulation of Rho protein signal transduction GO:0035024 ISO     negative regulation of Rho protein signal transduction GO:0035024 ISS     stress fiber assembly GO:0043149 ISO     stress fiber assembly GO:0043149 ISS     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 ISO     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 ISS     positive regulation of DNA replication GO:0045740 IEA     positive regulation of DNA replication GO:0045740 ISO     protein homooligomerization GO:0051260 IEA Subcellular Localization     nucleus GO:0005634 IEA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     endosome GO:0005768 ISO     endosome GO:0005768 ISS     Cul3-RING ubiquitin ligase complex GO:0031463 IBA     Cul3-RING ubiquitin ligase complex GO:0031463 ISO     Cul3-RING ubiquitin ligase complex GO:0031463 ISS