Gene description for Tsks
Gene name testis-specific serine kinase substrate
Gene symbol Tsks
Other names/aliases Stk22s1
Tssks1
Species Mus musculus
 Database cross references - Tsks
ExoCarta ExoCarta_22116
Entrez Gene 22116
UniProt O54887  
 Tsks identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tsks
Molecular Function
    protein kinase binding GO:0019901 ISO
Biological Process
    negative regulation of phosphatase activity GO:0010923 ISO
Subcellular Localization
    acrosomal vesicle GO:0001669 TAS
    cytoplasm GO:0005737 IEA
    centriole GO:0005814 ISO
    cytoskeleton GO:0005856 IEA
    cytoplasmic vesicle GO:0031410 IEA
 Experiment description of studies that identified Tsks in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tsks
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tsks is involved
No pathways found





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