|
 Gene description for Tuba1c |
| Gene name |
tubulin, alpha 1C |
| Gene symbol |
Tuba1c |
| Other names/aliases |
M[a]6
Tuba6 |
| Species |
Mus musculus |
| Database cross references - Tuba1c |
| ExoCarta |
ExoCarta_22146 |
| Entrez Gene |
22146 |
| UniProt |
P68373
|
| Tuba1c identified in exosomes derived from the following tissue/cell type |
|
Embryonic fibroblasts
|
18494037
|
|
Fibroblasts
|
23260141
|
|
Mast cells
|
17486113
|
|
Mov neuroglial cells
|
15210972
|
| Gene ontology annotations for Tuba1c |
|
|
| Experiment description of studies that identified Tuba1c in exosomes |
| 1 |
| Experiment ID |
73 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✔
HSP70|HSP90
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
18494037
|
| Organism |
Mus musculus |
| Experiment description |
Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. |
| Authors |
Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ |
| Journal name |
ELEC
|
| Publication year |
2008 |
| Sample |
Embryonic fibroblasts |
| Sample name |
NIH3T3 |
| Isolation/purification methods |
Differential centrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [LCQ DECA]
Western blotting |
|
|
| 2 |
| Experiment ID |
210 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✔
CD81|FLOT1
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
23260141
|
| Organism |
Mus musculus |
| Experiment description |
Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. |
| Authors |
Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL. |
| Journal name |
Cell
|
| Publication year |
2012 |
| Sample |
Fibroblasts |
| Sample name |
Normal-Fibroblasts (L cells) |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 3 |
| Experiment ID |
15 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✔
CD63
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
17486113
|
| Organism |
Mus musculus
Homo sapiens |
| Experiment description |
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. |
| Authors |
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO |
| Journal name |
NCB
|
| Publication year |
2007 |
| Sample |
Mast cells |
| Sample name |
MC9
Bone marrow-derived mast cells
HMC-1 |
| Isolation/purification methods |
Filtration
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.11-1.21 g/mL
|
| Molecules identified in the study |
Protein
mRNA
miRNA |
| Methods used in the study |
Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array |
|
|
| 4 |
| Experiment ID |
39 |
| ISEV standards |
|
✔
IEM
|
EV Biophysical techniques |
|
✔
TSG101|HSC70
|
EV Cytosolic markers |
|
✔
FLOT1
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
15210972
|
| Organism |
Mus musculus |
| Experiment description |
Cells release prions in association with exosomes. |
| Authors |
Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G |
| Journal name |
PNAS
|
| Publication year |
2004 |
| Sample |
Mov neuroglial cells |
| Sample name |
Mov neuroglial cell |
| Isolation/purification methods |
Differential centrifugation
Sucrose density gradient |
| Flotation density |
1.14 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy |
|
|
| Protein-protein interactions for Tuba1c |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
| Pathways in which Tuba1c is involved |
|
|
|
