Experiment description of studies that identified RANP1 in sEVs

1 Experiment ID 21 MISEV standards ✔ EM|IEM Biophysical techniques ✔ Alix|TSG101|HSP70|CD63 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry    PubMed ID 19837982     Organism Homo sapiens Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson" Journal name MCP Publication year 2009 Sample Colorectal cancer cells Sample name LIM1215 Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.10-1.12 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap] Western blotting

2 Experiment ID 219 MISEV standards ✔ EM Biophysical techniques ✔ CD63|CD9 Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25857718     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P" Journal name Int J Cancer Publication year 2015 Sample Nasopharyngeal carcinoma cells Sample name C666-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.17-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 220 MISEV standards ✔ EM Biophysical techniques ✔ CD63|CD9 Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25857718     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P" Journal name Int J Cancer Publication year 2015 Sample Nasopharyngeal carcinoma cells Sample name NP69 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.17-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 221 MISEV standards ✔ EM Biophysical techniques ✔ CD63|CD9 Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25857718     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P" Journal name Int J Cancer Publication year 2015 Sample Nasopharyngeal carcinoma cells Sample name NP460 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.17-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for RANP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PTCH1   Affinity Capture-MS Homo sapiens 2 HUWE1 10075 Affinity Capture-MS Homo sapiens View the network

Pathways in which RANP1 is involved

No pathways found