Gene description for Eif3l
Gene name eukaryotic translation initiation factor 3, subunit L
Gene symbol Eif3l
Other names/aliases 0610011H21Rik
Species Mus musculus
 Database cross references - Eif3l
ExoCarta ExoCarta_223691
Entrez Gene 223691
UniProt Q8QZY1  
 Eif3l identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Eif3l
Molecular Function
    protein binding GO:0005515 IPI
    translation initiation factor activity GO:0003743 ISO
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    translation GO:0006412 IEA
    translational initiation GO:0006413 ISO
Subcellular Localization
    fibrillar center GO:0001650 IDA
    cytoplasm GO:0005737 IEA
    eukaryotic translation initiation factor 3 complex GO:0005852 ISO
    nucleolus GO:0005730 IDA
    membrane GO:0016020 ISO
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified Eif3l in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Eif3l
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RRN3  
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which Eif3l is involved
No pathways found

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